Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry


A Simple and Efficient, Silica Supported Oxon Catalyzed One-pot Synthesis of 2-Aryl-Benzimidazoles

Author(s): Kumaraswamy G, Brahmeshwari G, Ravichander M, Jagadeesh Babu K, Srinivas B

A simple and efficient method for the synthesis of 2-arylbenzimidazole has been described involving the reaction of orthophenylene diamine with various primary alcohols using silicon supported Oxon as a catalyst. This method also describes mild reaction conditions, short reaction times, simple procedure, good yields and eco-friendly features.

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