Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Abstract

A validated RP-HPLC method for the quantification of Zolmitriptan in tablet dosage form

Author(s): Madhusudhanareddy Induri, Bhagavan Raju M, Rajendra Prasad Y, Pavankumar Reddy K, Rajkumar Boddu and Sarva Raidu Ch

A simple and rapid RP-HPLC method was developed for quantification of zolmitriptan in tablet dosage form. The chromatography system used a reversed phase C18 column with dual wavelength absorbance detection at 229 nm. The mobile phase consisted of acetonitrile and phosphate buffer (pH adjusted to 3.5 using ortho phosphoric acid) in the ratio of 10:90 % v/v at flow rate of 1.5 mL/min. The linearity range was found to be 10-50 μg/mL. The method was validated and it was concluded that the developed method was accurate, sensitive, precise, robust and useful for the quality control of zolmitriptan in pharmaceutical preparations


PDF

FIND ARTICLES
SCImago Journal & Country Rank
Recommended Conferences
bornova escort karşıyaka escort osmangazi escort buca escort anne porno fetiş porno anal porno bartın escort burdur escort eskişehir escort escort izmir bursa escort porno escort bayan