Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry


Alkylation of 2-substitutedquinazolin-4(3H)-one with DMF-DMA

Author(s): Mohammad Rafeeq*, Chittireddy Venkata Ramana Reddy and Pramod Kumar Dubey

We evaluated the potential of N,N-dimethylformamide dimethyl acetal (DMF-DMA) as a methylating agent for the preparation of 2-alkyl substituted quinazolin-4(3H)-one under solvent free condition.