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Amberlyst Ã?â??Ã?® 15 DRY Resin: A green and recyclable catalyst for facile and efficient one-pot synthesis of 3, 4-dihydropyrimidin-2(1H)-ones | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
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Abstract

Amberlyst Ã?â??Ã?® 15 DRY Resin: A green and recyclable catalyst for facile and efficient one-pot synthesis of 3, 4-dihydropyrimidin-2(1H)-ones

Author(s): Srinivasa Rao Jetti, Neelaiah Babu G., Pradeep Paliwal, Anjna Bhatewra, Tanuja Kadre, Shubha Jain

Ion exchange resin catalyzed multicomponent Biginelli reaction is studied for the synthesis of 3, 4-dihydropyrimidin-2-ones. Among the various solid acid catalysts Amberlyst® 15 DRY was found to be most efficient, recyclable and environmentally benign heterogeneous catalyst regarding reaction time, yield and ease of work up procedure.


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