Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Abstract

An efficient and clean synthesis of 2-(5-substituted-7-phenyl- [1,2,4]triazolo[4,3-f]pyrimidin-3-yl)quinoxalines

Author(s): T. Kranthi Kumar, T.Thirupathaiah, E. Laxminarayana and M. Thirumala Chary*

2-Mercapto-6-phenylpyrimidin-4-ol1, on reaction with POCl3 to afford 2,4-dichloro-6- phenylpyrimidine 2. Compound 2 on treating with quinoxaline-2-carbohydrazide 3 to furnish 2- (5-chloro-7-phenyl-[1,2,4]triazolo[4,3-f]pyrimidin-3-yl)quinoxaline 4. 2-(5-chloro-7-phenyl- [1,2,4]triazolo[4,3-f]pyrimidin-3-yl)quinoxaline 4 on treatment with different cyclic amines to yield 2-(5-substituted-7-phenyl-[1,2,4]triazolo[4,3-f]pyrimidin-3-yl)quinoxalines 5a-d. They have been screened for their antibacterial activity.


PDF

FIND ARTICLES
SCImago Journal & Country Rank
Recommended Conferences
bornova escort karşıyaka escort osmangazi escort buca escort anne porno fetiş porno anal porno bartın escort burdur escort eskişehir escort escort izmir bursa escort porno escort bayan