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An efficient synthesis of 2,4,6-triaryl pyridines and their biological evaluation | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
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Abstract

An efficient synthesis of 2,4,6-triaryl pyridines and their biological evaluation

Author(s): Seranthimata Samshuddin1, Badiadka Narayana1*, Divya N. Shetty1 and Ramappa Raghavendra

A simple and efficient synthesis of 2,4,6-triaryl pyridines with different substituents at 2- and 6- positions were described by one-pot condensation of 4,4’-difluoro chalcone, substituted acetophenones and ammonium acetate in glacial acetic acid. The newly synthesized compounds were characterized by elemental analysis, LCMS, FT-IR, and NMR spectroscopic data. All the compounds were evaluated for their antimicrobial and antioxidant activities.


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