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Analytical Description of 5-Nitroimidazole Derivative ├ó┬?┬?Satranidazole├ó┬?┬Ł | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
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Abstract

Analytical Description of 5-Nitroimidazole Derivative ├ó┬?┬?Satranidazole├ó┬?┬Ł

Author(s): Abhay Bhardwaj, Jyoti Sharma, Daksh Bhatia, Anuj Pathak, Nagarajan K, Jagannath Sahoo

Satranidazole is a type of antiprotozoal drug which belongs to the nitroimidazole group. It is highly effective, well accepted and clinically useful against protozoa. It is two times more active than other nitroimidazoles against amoebiasis and giardiasis. It is more active against anaerobes than other nitrogen containing imidazoles. Although much research work has been carried out on satranidazole regarding pharmacological screening and formulation development but till now structural description of satranidazole is not summarized in single literature text. The present study discusses the melting point, UV-Visible, Proton Nuclear Magnetic Resonance (1H-NMR), Mass, Fourier Transform Infra-Red (FTIR) data of satranidazole. Additional 13C-NMR was used to provide the maximum analytical details of structure of satranidazole.


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