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Analytical Method Development and Validation of Reslizumab In Bulk Drug and Pharmaceutical Dosage Form by Rp-Hplc Method | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
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Abstract

Analytical Method Development and Validation of Reslizumab In Bulk Drug and Pharmaceutical Dosage Form by Rp-Hplc Method

Author(s): L. Santosh kumar and P. Yadagiri Swamy*

A simple specific and accurate RP-HPLC method has been developed and validated for the estimation of Reslizumab in bulk drug and pharmaceutical dosage forms. The chromatographic conditions were viably created for the unit of Reslizumab by using Inertial - ODS C18 (250 x 4.6 mm,5μ), stream is 1.0 ml/min, convenient stage extent was Methanol: Water (75:25), recognizable proof wave length was 225 nm. Acetonitrile was used in this experiment. The results of the tablet analysis were validated with respect to accuracy (recovery), linearity, limit of detection (LOD) and Limit of quantitation (LOQ) were found to be satisfactory.


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