GET THE APP

Anti microbial study of newly formed complexes of transition and inner transition metals with antiulcer drug and RNA bases | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.

Abstract

Anti microbial study of newly formed complexes of transition and inner transition metals with antiulcer drug and RNA bases

Author(s): Sarika Verma, Sarita shrivastva and Poonam Rani

Binary and Ternary complexes of Transition metals (Co, Cu, Cr, Cd, Mn) and Inner transition metals (Th, Ce, Gd) have been synthesized by reacting their metal salts with antiulcer drug, namely Omeparazole (OME) and RNA bases namely Uracil(URA)/Adenine(ADE). The complexes are colored solids which are insoluble in cold water and freely soluble in DMF, DMSO and Ethanol. In this study, these metal complexes have been screened for their antibacterial activity towards Pseudomonas aeruginosa, Pseudomonas diminuta, Escherichia Coli , Streptococus Faecali Bacterias and antifungal activity towards Aspergillus Nidulans Fungi respectively .The results obtained were compared with that of the parent drug .The study reveals that the metal chelates (complexes) shows a remarkable resistance as compared with the parent drug.


PDF

Select your language of interest to view the total content in your interested language

30+ Million Readerbase
SCImago Journal & Country Rank
Google Scholar citation report
Citations : 23677

Der Pharma Chemica received 23677 citations as per Google Scholar report

Der Pharma Chemica peer review process verified at publons
Der Pharma Chemica- Journals on pharmaceutical chemistry