Anti oxidant activity of [6-chloro-2-(methylsulfanyl) pyrimidine-4-amine]cobalt(II)] complex | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.


Anti oxidant activity of [6-chloro-2-(methylsulfanyl) pyrimidine-4-amine]cobalt(II)] complex

Author(s): Suzan K. Oudah, Hassan T. Mohamed and Wasfi A. Al-Masoudi

Sodium nitrite is widely used as color fixative and preservative in meat and fish.Impairment of hepatic function and disturbances in lipid metabolism are well recognized advers effecte of sodium nitrite. The aim of this study is to investigate the role of [6 –chloro-2 (methylsulfanyl) pyrimidine -4-amine]cobalt(II)] complex, in preventing the oxidation of hemoglobline to methomoglobline in vitro, and preventing the disturbances in lipid metabolism induce by sodium nitrite toxicity in mice. The cobalt(II)complex of pyrimidine derivative causes inhibit sodium nitriteinduce methemoglobine formation, Moreover the complex cuases significant increase of total cholesterol, TG and LDL, while HDL significantly reduced.


Select your language of interest to view the total content in your interested language

30+ Million Readerbase
SCImago Journal & Country Rank
Google Scholar citation report
Citations : 25868

Der Pharma Chemica received 25868 citations as per Google Scholar report

Der Pharma Chemica peer review process verified at publons
Der Pharma Chemica- Journals on pharmaceutical chemistry