Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

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Abstract

Antibacterial and Antifungal Activities of the essential oil of Pulicaria jaubertii leaves

Author(s): Methaq Algabr, Nabil Al-Hajj, Ameerh Jaber, Amtellah Alshotobi, Shaima'a Al-suryhi, Gadah Whaban and Nawal Alshehari

Steam distillation of the essential oil of P. jauberti was performed using a Clevenger apparatus. Essential oils were analyzed by gas Gas Chromatography-flame ioziation detector (GC-FID) and Gas Chromatography coupled to chromatography–mass spectrometry (GC-MS). The majorchemical components identified in P. jaubertii essential oil include carvotanacetone (63.975%), 1-methyl-1,2-propanedione (5.887%), 2,5-dimethoxy-para-cymene (3.303%) and ar-curcumene (3.276%). The antimicrobial activity of the essential oil of P. jaubertii was evaluated against all tested microorganisms. P. jaubertii essential oil inhibited all tested microorganisms except Escherichia coli with a minimum inhibitory concentration (MIC) of 5.0 μg/mL against Staphylococcus aureus


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