The purpose of the present study is to evaluate the anti-inflammatory activity of the fresh extract obtained from the fruits Bougainvillea glabra Linn. in rats. The fresh juice extracted from the flowers of B. glabra Linn. were evaluated for the anti-inflammatory activity by using the carrageenan induced model in rats at a doses of 100 mg/kg and 200 mg/kg respectively. Biochemical parameters like paw oedema were studied. The B. glabra contains the phytochemical constituents like steroids. The fresh extract of B. glabra flowers showed the significant reduction in the paw volume at the doses of 100 mg/kg and 200 mg/kg. The results suggest that the flower extract of the Bougainvillea possess anti-inflammatory effect. The observed effect may be due to the presence of bioactive constituents.