Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry


Antimicrobial Activity and Microwave Assisted Synthesis of 1-(4-Chlorophenyl)-3,3-bis(methylthio)-2-(arylthio)prop-2-en-1-ones

Author(s): Anjaiah CH, Sunitha V, Abraham Lincoln CH, Ashok D

A series of arylsulfides have been synthesized by condensation of 1-(4-chlorophenyl)-3,3-bis(methylthio)prop-2-en-1-one with arylsulfonohydrazides in the presence of Iodine under microwave irradiation methods. All the compounds tested for their in vitro antimicrobial activity against bacterial and fungal organisms and they were characterized on the basis of spectral data such as IR, 1H-NMR, 13C-NMR and mass spectral data and elemental analysis.