Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

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Abstract

Antimicrobial activity and phytochemical studies on some Indian medicinal plants against selected human pathogens

Author(s): Selvamohan,T. MarakathaValli, T Sujitha,S

The acetone, ethanol, methanol extracts of 10 plants were evaluated for antimicrobial activity against medically important bacteria viz. Streptococcus sp., Staphylococcus sp., Klebsiella sp., E.coli, Salmonella sp., Pseudomonas sp., Candida sp. The invitro antimicrobial activity was performed by agar well diffusion method. The acetone and ethanol extracts were inactive compared to methanol extracts. The methanol extracts showed the maximum antimicrobial activity against the test organisms.Amongst the plant species screened, methanol extract of Indian aloe showed maximum inhibitory activity (44mm) against E. coli. The phyto-chemical analysis revealed the presence of tannins, glycosides, flavonoids, reducing sugars, anthraquinones


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