Eichhornia crassipes (Mart.) Solms, Waterhyacinth , once looked upon nonchalantly, has received supreme interest in recent years owing to its constructiveness in various fields. The solvent extracts of waterhaycinth was tested against a bacteria Staphylococcus albus by disc diffusion method and a fungal stains Mucor sp by streak plate method. Acetone extract evidenced better activity against the microbes among other extracts. The result adds to the value of the plant in pharmaceutical field as an antimicrobial agent.