Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry


Antioxidant Potential Study of some Synthesized N-Containing Benzothiazine Derivatives

Author(s): Damanjt Singh Cannoo, Simerpreet

Heterocycles having heteroatom N, S shows profound biological activities like antibacterial, antimicrobial, antihypertensive, anticancer etc. in addition to above said activities, a new series of synthesised compounds, 1,4-benzothiazine derivatives were found to show good antioxidant activity. To find the valuable bioactivity of above said ring transformed compounds, series of 4H-1,4-benzothiazine derivatives were synthesized through C-2 ring expansion of substituted 1,3-benzothiazoles. The antioxidant activities of all the synthesised compounds were screened by 2,2- Diphenyl-1-Picrylhydrazyl (DPPH) method having ascorbic acid as a standard. The synthesized compounds shows moderate to good antioxidant activity.


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