GET THE APP

Aqua mediated sodium acetate catalysed one-pot synthesis of pyrimidine derivatives as anti-inflammatory and antioxidant agent | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.

Abstract

Aqua mediated sodium acetate catalysed one-pot synthesis of pyrimidine derivatives as anti-inflammatory and antioxidant agent

Author(s): Dipen K. Sureja, Sandip P Dholakia and Kantilal R Vadalia

The present investigation is focused on one pot synthesis of 6-amino-5-cyano-4-substituted-2-(hydroxy/mercapto) pyrimidine derivatives with the objective of discovering a novel and potent anti-inflammatory and antioxidant agent. The formation of compounds was recognized by preliminary laboratory techniques like melting point, Rf value and further confirmed by spectral analysis. Furthermore, they were screened in-vitro to study their anti-inflammatory and antioxidant activity, which shows moderate to good potency.


PDF

Select your language of interest to view the total content in your interested language

30+ Million Readerbase
SCImago Journal & Country Rank
Google Scholar citation report
Citations : 23677

Der Pharma Chemica received 23677 citations as per Google Scholar report

Der Pharma Chemica peer review process verified at publons
Der Pharma Chemica- Journals on pharmaceutical chemistry