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Aqueous phase synthesis of substituted imidazo[1,2-a]pyridine in the presence of ?²-cyclodextrin | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
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Abstract

Aqueous phase synthesis of substituted imidazo[1,2-a]pyridine in the presence of ?²-cyclodextrin

Author(s): Vijay V. Kumbhar, Shankar P. Hangirgekar and Navanand B. Wadwale

A simple and practical procedure for aqueous phase reaction of various α-tosyloxy ketones with 2- amino pyridine and their derivatives in the presence of β-Cyclodextrin has been developed to furnish bridgehead azaheterocycles 3a-h & 4a-d in good to excellent yields.


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