Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry


Aqueous phase synthesis of substituted imidazo[1,2-a]pyridine in the presence of β-cyclodextrin

Author(s): Vijay V. Kumbhar, Shankar P. Hangirgekar and Navanand B. Wadwale

A simple and practical procedure for aqueous phase reaction of various α-tosyloxy ketones with 2- amino pyridine and their derivatives in the presence of β-Cyclodextrin has been developed to furnish bridgehead azaheterocycles 3a-h & 4a-d in good to excellent yields.