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Biochemical analysis and structure elucidation of ?±- Campholene aldehyde from marine sponge-derived Aspergillus terreus MP1 | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
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Abstract

Biochemical analysis and structure elucidation of ?±- Campholene aldehyde from marine sponge-derived Aspergillus terreus MP1

Author(s): J. Meenupriya, Atlanta majumdar, Antojasmine jenifer, Udaya britto, M. Thangaraj

Non destructive by-catch collection of Sponges from south Indian coastal belts yielded four novel strains of Aspergillus species; among which Aspergillus terreus MP1 strain yielded interesting bioactivity against potent human pathogens and cancer cell lines. The chemical moieties responsible for the bioactivity were identified using GC-MS analysis as 15-methyl, tricycle[6.5.2(13,14).0(7,15)]pentadeca-1,3,5,7,9,11,13-heptene with molecular formulaC16H14 with molecular weight 206 Da, 3,4-Dihydro-2H-1,5-(3-t-butyl)benzodioxepine with molecular formulaC13H18O2 with molecular weight 206 Da, 2,6-dimethyl-N-(2-methyl-α- phenylbenzyl)aniline with molecular formulaC22H23N with molecular weight 301 Da as α- Campholene aldehyde with Chemical formula C10 H16 O with molecular weight 152 Da. α- Campholene aldehyde has an already known 3D structure whereas the other three compounds are novel .


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