Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

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Abstract

Biological activity of drug like small molecules based on quinoxaline containing amino substitution at C-2

Author(s): K. Raghavendra Raoa, Akula Raghunadha, Dipak Kalitaa, Eppakayala Laxminarayanab, Manojit Palc and Suresh Babu Meruva

A series of novel “drug like” small molecules based quinoxaline containing amino substitution at C-2were synthesized. The strategy used is simple, efficient and afforded good yields of quinoxaline derivatives. The biological activity of these quinoxaline derivatives for PDE4B enzyme inhibition with reference to rolipram have been reported.


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