Biosorption of Cadmium and Zinc by Tanjung Fruit Husk (Mimusops elengi L.) has been studied. Some parameters were donesuch as pH effect, solution concentration, contact time, biosorbent mass, and particle size. The optimum conditions for Cd ion were at pH 5, concentration 900 mg/L, contact time 15 minutes, biosorbent mass 0.1 g, particle size 32 μm, at room temperature. The optimum conditions for Zn ion were at pH 6, concentration 1000 mg/L, contact time 30 minutes, biosorbent mass 0.1 g, particle size 32 μm, and heat temperature of biosorbent 25 oC. Adsorption capacity (qe) at the optimum condition for Cd and Zn ion were 6.95 mg/g and 14.51 mg/g, respectively. Adsorption isotherm for both metal ions followed Freundlich isotherm mechanism model with R2 for Cd and Zn ion were 0.8851 and 0.9202, respectively.Analysis of functional group in biosorbent was used FTIR that might revealed –OH stretching, C-H stretching, C=O stretching, and C-O stretchinggroupwith wave numbers were 3419.97; 2922.60; 1617.47; and 1034.99 cm-1. Morphology of biosorbent surface was analyzed using SEM.