Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

Abstract

Carboxylic Acids and Amino Acids of Galium pseudomollugo Herb

Author(s): Tetyana V Ilina, Olga V Goryacha, Ala M Kovalyova, Oleh M Koshovyi

In Galium pseudomollugo Klokov herb, by means of gas chromatography-mass spectrometry 30 carboxylic acids have been identified and quantified, including 23 monobasic acids, 6 dibasic acids and 1 tribasic acid. By the radical linked to the carboxyl group, the acids were classified as 9 aromatic acids and 21 aliphatic acids, including 12 fatty acids, 9 of which were saturated and 3 unsaturated; 1 keto acid was identified. The dominant was levulinic acid. By HPLC in G. pseudomollugo herb 21 amino acids have been identified; the free amino acid content equaled 0.98%, 0.25% of which fell on essential amino acids, whereas the content of bound amino acids amounted to 5.75%, 2.51% of which fell on essential amino acids. Identified as prevailing in the total amino acid content were aspartic acid, glutamic acid and proline. Dominant among free amino acids were aspartic acid, asparagine and proline.


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