Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

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Chemical Compounds, Antibacterial and Insecticidal Activity of Lipophilic Extract of Scrophularia amplexicaulis Benth and Scrophularia oxysepala Boiss

Author(s): Ardalan Pasdaran, Arsalan Pasdaran, Maria Atanassova, Mohammad Ayaz Ahmad

Chemical compounds of the hydrophobic extracts (n-hexane-ether extract) of the aerial parts of Scrophularia amplexicaulis and Scrophularia oxysepala were analyzed for the first time by the Gas Chromatography-Mass Spectrometry (GC-MS) and Gas Chromatography-Flame Ionization Detection (GC-FID). Total 36 compounds were identified which were 84.7% and 79.8% of total compounds of then-hexane-ether extract. The main constituents were n-Dotriacontane (15.1%), 1-Docosanol (13.6%), Eicosane (11.6%) in S. oxysepala and n-Pentatriacontane (32.9%), n-Tetrateracontane (16.8%) and Gamma-Sitostrol (8.7%) in S. amplexicaulis. The antibacterial was tested using the inhibition of broth dilution with shaking (BDS) method and contact toxicity assay indicated by calculation of percentage mortality of insects based on Isman method.

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