Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry


Chemical Compounds, Antibacterial and Insecticidal Activity of Lipophilic Extract of Scrophularia amplexicaulis Benth and Scrophularia oxysepala Boiss

Author(s): Ardalan Pasdaran, Arsalan Pasdaran, Maria Atanassova, Mohammad Ayaz Ahmad

Chemical compounds of the hydrophobic extracts (n-hexane-ether extract) of the aerial parts of Scrophularia amplexicaulis and Scrophularia oxysepala were analyzed for the first time by the Gas Chromatography-Mass Spectrometry (GC-MS) and Gas Chromatography-Flame Ionization Detection (GC-FID). Total 36 compounds were identified which were 84.7% and 79.8% of total compounds of then-hexane-ether extract. The main constituents were n-Dotriacontane (15.1%), 1-Docosanol (13.6%), Eicosane (11.6%) in S. oxysepala and n-Pentatriacontane (32.9%), n-Tetrateracontane (16.8%) and Gamma-Sitostrol (8.7%) in S. amplexicaulis. The antibacterial was tested using the inhibition of broth dilution with shaking (BDS) method and contact toxicity assay indicated by calculation of percentage mortality of insects based on Isman method.

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