Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

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Comparative anti microbial studies of aqueous, methanolic and saponins extract of seeds of Trigonella Foenum-Graecum on human vaginal pathogens causing UTI infection

Author(s): Raghvendra Dubey, Kushagra Dubey, Yasodha Krishna Janapati, C. Sridhar4 and K. N. Jayaveera

The aqueous, methanolic and saponin extracts of Trigonella foenum-Graecum seeds were screened for antimicrobial activities against some human vaginal pathogens Staphylococcus aureus, Pseudomonas aeruginosa, streptococcus facecalis, klebsiella pneumoniae, Escherichia coli, Enterobacter faecalis, Enterobacter faecium and Proteus mirabilis isolated from patient samples. Extracts were found to produce significant inhibition against all the pathogens. Saponin extract were observed to be more active than methanolic and aqueous fraction. Extracts are found to be more active against klebsiella pneumoniae, Escherichia coli, Pseudomonas aeruginosa and Enterobacter faecalis strains.


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