Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

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Abstract

Composition and antimicrobial activity of the essential oil of Hyssopus seravschanicus growing wild in Tajikistan

Author(s): Farukh S. Sharopova=, Mukhamadsho A. Kukaniev, Rachel M. Thompson, Prabodh Satyal, William N. Setzer

The volatile compounds from Hyssopus seravschanicus Pazij, a plant growing wildly near the high ridge mountainous regions of Varzob, Northern Dushanbe in Tajikistan at an altitude approximately 2500 meters above sea level, were extracted and analyzed using gas chromatography-mass spectrometry (GC-MS). Eighty-seven chemical components of the essential oil were found and characterized representing approximately 95.4% of the oil. The most abundant components were cis-pinocamphone (57.0-88.9%), β-pinene (0.4-6.0%), 1,8-cineole (1.8-3.6%), camphor (0.5-4.0%), and spathulenol (0.1-5.0%). The essential oil from Hyssopus seravschanicus showed notable antimicrobial activity against Bacillus cereus and Staphylococcus aureus.


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