A series of classical Dihydropyrimidone (DHP) derivatives were synthesize from o-hydroxy aldehydes. Azosalicyaldehydes were prepared from various substituted anilines with salicylaldehyde by the reported process. These Azosalicyaldehydes were reacts with ethylacetoacetate and urea in presence of ZnCl2 catalyst under 70-80°C temperature gives reported DHP products rather than oxygen bridged tricyclic product. The present method is founds eco-friendly, highly efficient, and clean method for the selective synthesis of DHP derivatives.
Select your language of interest to view the total content in your interested language
Der Pharma Chemica received 11575 citations as per Google Scholar report