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Design, Synthesis, and characterization of a novel Ciprofloxacin-Antioxidant mutual prodrugs | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X

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Abstract

Design, Synthesis, and characterization of a novel Ciprofloxacin-Antioxidant mutual prodrugs

Author(s): Ahmed K. Hussein, Noor H. Nasser, Abbas H. Abdulsada and Samer A. Hasan

A novel Prodrugs (Compounds I and II) have been designed, and synthesized, in which ciprofloxacin has been linked to two different anti-oxidants using chloroacetylchloride as spacer. These prodrugs have been characterized by various physico-chemical methods like melting points, Rf values, and FT-IR spectrum.


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