GET THE APP

Determination of Genotoxic Alkyl Paratoluene Sulfonates in Brinzolamide Using RP-LC | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X

ilbet

süperbetin giriş

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.

agariookey oyna istanbul okey

Abstract

Determination of Genotoxic Alkyl Paratoluene Sulfonates in Brinzolamide Using RP-LC

Author(s): Anil Shahaji Khile, Subba Rao M, Ramachandran D

Highly sensitive method for the determination of genotoxic impurities such as Alkyl Para Toluene Sulfonates (APTSs) in brinzolamide using RP-LC has been presented in the present paper. APTSs were determined by RP-LC method using Waters Symmetry C18 (250 × 4.6 mm), 5 μ column as stationary phase. Column temperature maintained 30°C, injection volume 20 μl, flow rare was 1.5 ml/min, sample cooler temperature 5°C and run time was 30 min. pH 2.50 phosphate buffer is used. The mixture of buffer and acetonitrile in 50:50 (v/v) was used as mobile phase. The method validation has been carried as per International Conference on Harmonization guidelines. Limit of Quantitation (LOQ) was found in the range of 1.1-2.2 μg/ml for APTSs.


PDF

rokettube brazzers

paper.io

agar io

wowcappadocia.com
cappadocia-hotels.com
balloon-rides.net

wormax io

Smok
Elektronik Sigara