Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
Abstract
Development and validation of kinetic spectrophotometric method for the determination of lamivudine in pure and commercial tablets
Author(s): Kareem M YounesA rapid, simple and sensitive spectrophotometric method for the determination of lamivudine has been developed and validated. The method is based on oxidation of lamivudine with alkaline potassium permanganate. The reaction is kinetically studied by measuring the rate of change of absorbance at 610nm. The rate constant, fixed absorbance and fixed time methods are investigated. Only the fixed time method is utilized for construction of calibration graph to determine the concentration of the studied drug. The results are validated statistically and checked through recovery studies. The method has been successfully applied for the determination of lamivudine in its commercial dosage form.
Select your language of interest to view the total content in your interested language
Google Scholar citation report
Citations : 25868
Der Pharma Chemica received 25868 citations as per Google Scholar report
Der Pharma Chemica peer review process verified at publons
DOWNLOADS
