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Efficient one pot, three-component synthesis of new ├?┬▒-aminophosphonates and investigation of their antimicrobial activity | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X

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Abstract

Efficient one pot, three-component synthesis of new ├?┬▒-aminophosphonates and investigation of their antimicrobial activity

Author(s): Amulrao U. Borsea,Nilesh L. Patila, Mahesh N. Patila and Raghav S. Malib

A convenient one pot synthesis of new α-aminophosphonates (4a-h) containing ethyl acetate moiety was accomplished via Kabachnik-Fields reactions in good yield. All synthesized compounds were characterized by IR, 1H NMR, 13C NMR, 31P NMR and Mass spectroscopy and investigated their antimicrobial activity


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