A series of synthesized benzophenones possessing pyridine nucleus 8a–l were evaluated for antioxidant activity by in vitro studies through different in vitro models such as DPPH, nitric oxide and hydrogen peroxide free radicalscavenging activity. The antioxidant activity result shows that compound 8k with hydroxy and methyl groups exhibited highest activity. Compounds 8l with amino and methyl groups has shown second highest activity. Further, compounds 8b with fluoro and hydroxy groups, 8e with chloro and hydroxy groups and 8h with iodo and hydroxy groups also exhibited activity next to compounds 8k and 8l..
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