Evaluation of Phytochemicals Profile and Antioxidant Activities of Asperagus racemosus using in vitro and in silico Approach | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
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Evaluation of Phytochemicals Profile and Antioxidant Activities of Asperagus racemosus using in vitro and in silico Approach

Author(s): Lalit Samant*

Asparagus racemosus belongs to family Liliaceae and commonly known as Satawar, Satamuli, Satavari. A. racemosus is an important medicinal plant and its root paste or root juice has been used in various ailments and as health tonic. The management of burn wound victims is often considered a difficult task due to frequent infections. Moreover, the treatment with conventional antibiotics is associated with the upsurge of drug resistant bacterial strains; for the current study, A. Racemosus was collected, authenticated, and subjected for the preparation of extracts using ethanol as solvent for extracting phyto constitutes present in them. Further in Phytochemical analysis of Asparagus racemosus the quantitative estimation of phenolic and flavonoid content was done. Results obtained were TPC (Total Phenolic Content) and TFC (Total Flavonoid Content) 22.2514 µg GAE/mg and 5.5028 µg QE/mg respectively which showed the presence of good amount of phenolic and flavonoid content. In chemical analysis the plant extract was analysed via. GC-MS and FTIR. The GC-MS study showed many Phytochemicals such as Hydroxypyranone, Tetradecanoic acid, Octadecadienoic acid, n-Hexadecanic acid etc. (24 compounds). These compounds show antimicrobial, antitumor, anticonvulsant, anti-inflammatory and ty-rosinase inhibitory effects, Anticancer, Antioxidant properties. The FTIR analysis of ethanol plant extracts of A. racemosus confirmed the presence of alcohols, phenols, alkanes, carboxylic acids, alkenes, aromatics, esters, ethers, allenes compounds etc., which showed major peaks.


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