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Evaluation of some enzymes levels in Iraqi children infected with visceral leishmaniasis | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
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Abstract

Evaluation of some enzymes levels in Iraqi children infected with visceral leishmaniasis

Author(s): Jasim Hameed Taher 1 , Noor Al-huda Abdullah 2 , Sura Mohammad 2 and Eman Faris 2

The study was carried out to evaluate some biochemi cal aspects which were performed on blood samples o f visceral leishmaniasis (VL) and control group . Fifty blood samples were confirmed parasitologically by immunochromatography (IC) with rk - 39 antigen stri ps test and their applications . Ten samples for co ntrol were obtained from apparently healthy children . The res ults of enzymes showed that there was a significant increase (P < 0.05) in the levels of adenosine deaminase (ADA), glutathione reductase (GHR) and superoxide dismuta se (SOD) in VL patients compared to the healthy control grou p . The mean levels of hepatic enzymes; alkaline ph osphatase (ALP), lactate dehydrogenase (LD), alanine aminotra nsferase (ALT) and aspartate aminotransferase (AST) exhibited a significant elevation (P < 0.05) in VL patients compared to the control .


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