GET THE APP

Exploration of Spectral, Thermal, Antibacterial and Antioxidant Activities of newly synthesized inclusion complexes of N-(3-Phenylallylidine) and N-(3- isopropylbenzylidene)-(1, 3, 4) Thiadiazino[6, 5b]Indole-3-amine with ?²-CD | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.

Abstract

Exploration of Spectral, Thermal, Antibacterial and Antioxidant Activities of newly synthesized inclusion complexes of N-(3-Phenylallylidine) and N-(3- isopropylbenzylidene)-(1, 3, 4) Thiadiazino[6, 5b]Indole-3-amine with ?²-CD

Author(s): Rabinarayana Sahu, Pramod Kumar Das and Bamakanta Garnaik

In the context of the present medicinal advancement, the research has been carried out to synthesize and improvise some Indole derivatives having pharmacological activity through inclusion complex formation with β-cyclodextrin. The thermodynamic stability of the inclusion complexes are determined by studying different parameters such as free energy change and stability constant. The compounds and their inclusion complexes are characterized on the basis of physical and spectral analysis (UV,FT-IR,1HNMR). The biological screening was done against three bacterial strains i.e E.Coli, S.aureus and P. Vulgaris in order to explore their vital antimicrobial activities. The antioxidant activities are also studied. Both the antibacterial and antioxidant activities are noticeably enhanced after encapsulation into the cavity of β-cyclodextrin.


PDF

Select your language of interest to view the total content in your interested language

30+ Million Readerbase
SCImago Journal & Country Rank
Recommended Conferences
Google Scholar citation report
Citations : 23677

Der Pharma Chemica received 23677 citations as per Google Scholar report

Der Pharma Chemica peer review process verified at publons
Der Pharma Chemica- Journals on pharmaceutical chemistry