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Facile and green syntheses of substituted-5-arylidene-2,4-thiazolidinediones using L-tyrosine as an Eco-Friendly catalyst in aqueous medium | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X

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Abstract

Facile and green syntheses of substituted-5-arylidene-2,4-thiazolidinediones using L-tyrosine as an Eco-Friendly catalyst in aqueous medium

Author(s): G. Thirupathi, M. Venkatanarayana, P. K. Dubey and Y. Bharathi Kumari

L-tyrosine has been utilized as an efficient catalyst for the Knoevenagel condensation of arylaldehydes 1(a-k) with 2,4-thiazolidinedione(2) containing cyclic active methylene group in aqueous medium at room temperature to afford substituted -5-arylidene-2,4-thiazolidinediones 3(a-k)


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