Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

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Flavonoid glycosides from Periploca laevigata (Asclepiadaceae) from Algeria

Author(s): Samia Mezhoud, Hanane Aïssaoui, Séverine Derbré, Ratiba Mekkiou, Pascal Richaume, Samir Benayache and Fadila Benayache

The phytochemical investigation of the n-butanol extract of aerial parts of Periploca laevigata resulted in the isolation of four known compounds, kaempferol 3-O-β-arabinopyranoside (1), kaempferol 3-O-β-glucopyranoside (2), quercetin 3-O-arabinopyranoside (3) and quercetin 3-O-rutinoside (4). The structures of the compounds were determined on the basis of extensive spectroscopic analysis, including 1D and 2D NMR as well as acid hydrolysis and comparison with the related known compounds.


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