Flavonoids glycosides from leaves of Catha edulis (Celasteraceae) | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X


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Flavonoids glycosides from leaves of Catha edulis (Celasteraceae)

Author(s): 1,3 Methaq Algabr*, 2 Abdul-malik Abu Dunia, 1 Hanane Aissaoui, 1 Leila Hammoud, 1 Ratiba Mekkiou, 1 Samir Benayache and 1 Fadila Benayache

Five flavonoid glycosides having kaempferol 3 , quercetin 4 and myricetin 2 , 5 and 6 skeleton were isolated from leaves of Catha edulis species together with querce tin. The structure of ampelopsin ( 2) , was assigned by combination on 1D and 2D NMR spectroscopy for the f irst time as well as MSESI. While the structures of kaempferol 3-O- β -Glucopyranoside (3) , Quercetin 3-O- β - Galactopyranoside(4) , Myricetin 3-O- β - Glucopyranoside (5) and Myricetin 3-O- β -Xylofuranoside ( 6) were identified by 1 H and 13 C NMR, as well as UV spectroscopy and also confirmed by the spectral dat a of aglycones and TLC of the sugars obtained after acid hydrolysis. Compounds 3 , 5 and 6 were reported for the first time from this plant.


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