Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry


GC-MS Analysis and Antimicrobial Activity of Solvent Extracts of Zizyphus lotus (L.) Desf.

Author(s): E. Chebouat, N. Gherraf, B. Dadamoussa, M. Allaoui and A. Chirite

Dichloromethane profile of the fruits of Zizyphus lotus (Rhamnaceae) growing in Algeria was studied by capillary gas chromatography-mass spectrometry (GC-MS). 21 compounds were identified among which: Heptadecene- (8)-Carbonicacid(40.22%),9-Octadecenoicacid(z)-ethylester(16.94%), hexadecanoic acid (9.14%), Phenol, 2-(2-aminoethyl)(6.19%), Ethyl linoleate (3.94%) and Hexadecanoic acid, ethyl ester (3.23%). Moreover, the antibacterial activities of the ethyl acetate extract of Zizyphus lotus were tested against standard bacterial strains: Serratia marcescens ATCC 13880 , Pseudomonas aeruginosa ATCC 10145 , Bacillus subtilis ATCC 6051 , Escherichia coli ATCC 25922 , Enterococcus faecalis ATCC 29212 , Staphylococcus aureus ATCC 25923 and Bacillus cereus ATCC 11778 using both disc diffusion and dilution methods .