Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
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Abstract
HBF4: SiO2: An efficient heterogeneous catalyst for the one step synthesis of 4(3H)-quinazolinones under solvent free conditions
Author(s): Keetha Laxminarayana, Chinnapillai Rajendiran, Khagga MukkantiThe one pot synthesis of 3-Substituted quinazolinones derivatives prepared from anthranalic acid, substituted amines and triethylorthoformate in presence of HBF4.SiO2 as catalyst has been described. The reaction proceeded with in few minutes with excellent yields. The simple experimental procedure and reusability of the catalyst are significant advantages of this protocol.
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