Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry


Highly Efficient Recylable ZnO Nanoparticles Catalyst Bio-Derived from Solanum xanthocarpum Berry Extract for the Synthesis of some Schiff Base Derivatives

Author(s): Muthukumar S, Kalyanasundaram S, Santhanalakshmi K, Jacquline Rosy P

The green, ecofriendly production of ZnO nanoparticles using Solanum xanthocarpum berry extract and their use as a nanocatalyst in the synthesis of substituted Schiff base derivatives. Bio-synthesized nanoparticles were characterized by X-rey Diffraction (XRD), Scanning Electron Microscope (SEM), Elementary Dispersive X-ray (EDX), Infra-Red (IR) and Transmission Electron Microscopy (TEM) techniques. Bio-derived ZnO nanoparticles are efficiently utilized in the synthesis of Schiff base derivatives (3a-e) from 2-amino-5-fluorobenzonitrile and substituted benzaldehydes in the presence of ultrasound irradiation with high yields. The catalyst can be removed and recycled several times without marked loss of activity.