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IDENTIFICATION AND QUANTIFICATION OF DM DM HYDANTOIN IN SELECTED SHAMPOOS | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
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Abstract

IDENTIFICATION AND QUANTIFICATION OF DM DM HYDANTOIN IN SELECTED SHAMPOOS

Author(s): Anusree V, Shebina P Rashee*, Basil Mohammed K.P, Thasleena V.P, Parvathy S.L .Muhammed Khais

DM DM hydantoin is a formaldehyde releaser, used in cosmetic products at concentrations up to 1.0%. It is found in products like shampoos, hair conditioners, hair gels, Rite Aid Liquid Lubricant, and skin care products. The present study is an attempt to develop a rapid but simple spectrophotometric method in the UV/ visible mode for the identification and quantification of DM DM hydantoin in cosmetic products like shampoos to aid regulatory agencies confirm manufacture’s substantiation claims. Here, we use different brands of shampoos are selected and comparative study is made using the developed spectrophotometric method using ethanol solvent. By comparing the 4 samples (A, B, C, D) of shampoos with a selected standard shampoo, the concentration and percentage content of the different samples were calculated. The quantified amount (mg/ml) of DM DM Hydantoin were 1.7 ± 0.0124, 0.541 ± 0.0011, 1.956 ± 0.0132, 0.245 ± 0.00045, 0.3810 ± 0.00071 in standard and samples A, B, C, D respectively. The percentage content is low in sample C and high in sample B while comparing with the standard sample. This method can be utilize in industry to determine preservative content.


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