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Improved process for the preparation A Long-acting ├?┬▓2-adrenergic agonist (LABA) Salmeterol and identification, characterization and control of its potential process impurity
Author(s): Sahadeva Reddy, Rajan ST, Parusuramudu, Raghupathi Reddy and Chakravarthy IE
An improved and commercial viable process for the active pharmaceutical ingredient of new Long-acting β2- adrenergic agonist (LABA) Salmeterol has been developed. This improved process includes the isolation of Salmeterol 1 and identification, controlling and synthesis of its potential Diether impurity 2.