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Improved process for the preparation A Long-acting ?²2-adrenergic agonist (LABA) Salmeterol and identification, characterization and control of its potential process impurity | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
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Abstract

Improved process for the preparation A Long-acting ?²2-adrenergic agonist (LABA) Salmeterol and identification, characterization and control of its potential process impurity

Author(s): Sahadeva Reddy, Rajan ST, Parusuramudu, Raghupathi Reddy and Chakravarthy IE

An improved and commercial viable process for the active pharmaceutical ingredient of new Long-acting β2- adrenergic agonist (LABA) Salmeterol has been developed. This improved process includes the isolation of Salmeterol 1 and identification, controlling and synthesis of its potential Diether impurity 2.


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