In vitro antibacterial and antifungal evaluation of some benzophenone analogues | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.


In vitro antibacterial and antifungal evaluation of some benzophenone analogues

Author(s): Mohammed Al-Ghorbani, Lakshmi Ranganatha V, Prashanth T, Bushra Begum A. and Shaukath Ara Khanum

Antibacterial and antifungal agents are widely used in the management of infectious disease but most of them have developed resistance to micro-organism. To overcome this problem and to lower the side effects, many approaches can be utilized. Benzophenone derivatives are reported to have the broad spectrum of biological activities. In the present study we have screened benzophenone derivatives 5a-k against six bacterial species viz gram positive (Bacillus subtilis and Staphylococcus aureus) and gram negative (Pseudomonas aeruginosa, Salmonella typhi, Proteus vulgaris, Shigella flexneri) bacteria. Also compounds 5a-k were tested with six fungal species viz (Candida albicans, Aspergillus niger, Fusarium solani, Aspergillus flavus, Botrytis cinerea, Candida krusei). The obtained results showed that the synthesized compounds 5a-k exhibited moderate to good activities against all the tested strains. Compounds 5a, 5c, 5d, 5f and 5g have shown good antibacterial and antifungal activities against selected strains.


Select your language of interest to view the total content in your interested language

30+ Million Readerbase
SCImago Journal & Country Rank
Google Scholar citation report
Citations : 25868

Der Pharma Chemica received 25868 citations as per Google Scholar report

Der Pharma Chemica peer review process verified at publons
Der Pharma Chemica- Journals on pharmaceutical chemistry