Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Abstract

In vitro antileishmanial activity of Khinjuk essential oil against Leishmania major promastigotes

Author(s): Hossein Mahmoudvand, Sareh Jahanbakhsh and Farzad Doostishoar

The present study aims to assess the in vitro antileishmanial activity of Myrtle (Pistacia khinjuk) essential oil against Leishmania major promastigotes. The in vitro antileishmanial effects of Khinjuk essential oil against L. major promastigotes were performed using MTT method. The IC50 values were also calculated by Probit test in SPSS software. The obtained results showed that myrtle extract was significantly inhibited promastigote growth of L. major based on a dose and time dependent manner. The measured IC50 values for Khinjuk essential oil and MA as control drug against promastigote forms of L. major were 8.9 μl/mL and 44.6 μg/mL, respectively. The obtained results showed antileishmanial effects of Khinjuk against promastigote forms of L. major. However, further studies will be needed to confirm these results by checking in the animal models as well as volunteer human.


PDF

FIND ARTICLES
SCImago Journal & Country Rank
Recommended Conferences
bornova escort karşıyaka escort osmangazi escort buca escort anne porno fetiş porno anal porno bartın escort burdur escort eskişehir escort escort izmir bursa escort porno escort bayan