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In-Vitro Study on Anti-Urolithiatic of Brassica Oleracea Var Capitata Linn | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X

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Abstract

In-Vitro Study on Anti-Urolithiatic of Brassica Oleracea Var Capitata Linn

Author(s): Rajeshwari Pasupula, Hawi Matewos, Gamechu Gurumu and Mohammed

Background: Urolithiasis is a condition that is caused by the formation of urinary calculi in the renal tubule; it can be defined as the formation of crystals in the urinary tract. Around 4% - 15% of the world population suffers from urinary stones. Urolithiasis is caused by many different factors such as heredity, diet, metabolic abnormality, infection, and slightly by age, gender and climate.

Method: The methodologies used to perform this study in-vitro anti-urolithiatic activity analysis by performing microscopic growth of calcium oxalate stone, nucleation assay and aggregation assay on Brassica oleracea var. capitata Linn.

Result: The inhibition of crystal growth by the plant extract is in a dose dependent manner (P< 0.05).

Conclusion: The anti-urolithiatic activity of Brassica oleracea var. capitata Linn was experimentally proven.


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