GET THE APP

Ionotropic Glutamate Receptor Subtype 6: Docking and Site Moiety Map Analysis Study | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X

ilbet

süperbetin giriş

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.

agariookey oyna istanbul okey

Abstract

Ionotropic Glutamate Receptor Subtype 6: Docking and Site Moiety Map Analysis Study

Author(s): Ashwani Kumar, Anupama, Sandeep Jain

In an attempt to discover more potent ligands, we present here a docking study for ionotropic glutamate receptor subtype 6 which is important in many neurodegenerative diseases. Total 97 compounds including a small series of commercially available compounds are characterized in iGluR6 binding. Z-scores were employed to recognize hits for this receptor. Twenty eight compounds were shown to have excellent binding affinity on this target. A detailed in silico study showed the strong interactions of compound no. 2h and 13515655 with iGluR6. Total four anchors were found. They involve three hydrogen bonding interactions and one vander waal interaction.


PDF

Select your language of interest to view the total content in your interested language

30+ Million Readerbase
SCImago Journal & Country Rank
Recommended Conferences
Google Scholar citation report
Citations : 11575

Der Pharma Chemica received 11575 citations as per Google Scholar report

Der Pharma Chemica peer review process verified at publons

rokettube brazzers

Turkish dental care is known to be affordable compared to other countries. If you want an affordible dentist Turkey, check out periodonta. It is heavily recommended for dental patients visiting Turkey