Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry


Kinetics of Micelle catalyzed Oxidation of m-Toluidine

Author(s): Firoz Ahmad, Ritu Singh* and Farhat Hasan Khan

The Oxidation of m-Toluidine by Cr(VI) has been studied both spectro-photometrically (640 nm) and Iodometrically in aqueous nitric acid medium in presence of micelles (CPC, Cetyl Pyridinium Chloride; Tween-20, Polyoxyethylene Sorbitan Monolaurate) and is said to follow a consecutive reaction mechanism. Kinetic parameter can not be calculated from absorbance data because absorbance after showing maximum showed marginal dip indicating that the decomposition of colored product is slow. Reaction is retarded by both the surfactant. At high concentration of detergents, the Toluidine concentration had no effect on the reaction rate. Mechanism with the associated reaction kinetics is assigned and discussed.