Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

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Linagliptin: A Concise Review on Analytical and Bio-analytical Methods

Author(s): Bassam M. Ayoub

The presented work is a collective review of the previously published methods concerning the analysis of linagliptin either alone or in binary mixture with metformin. Many spectroscopic and chromatographic techniques were used for linagliptin analysis either in biological fluids or in pharmaceutical formulations including spectrophotometry, spectrofluorimetry, HPLC-UV, LC-MS/MS and HPTLC methods. This review can be used as a guide for analysts to select the most appropriate method for their work


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