Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Abstract

Manufacture of a Slow Release Herbicide of Methyl-Metsulfuron using biopolymer of Poly (3-hydroxybutyrate) as Matrix

Author(s): Anthoni Agustien, Kartika Sari, Armini, Annajmiyatul Fitria and Akmal Djamaan

The formulation of microcapsule of methyl-metsulfuron using biopolymer of poly(3-hydroxy-butyrate) as matrix of herbicide by solvent evaporation technique has been carried out. In the study, three types of the microcapsule formulation was used with the ratio between methyl-metsulfuron, and poly(3-hydroxybutyrate) of 2:1, 1:1, and 1:2 respectively. The particle distribution was measured using a calibrated microscope. Active substance release was determined by UV-Vis spectrophotometer. Results indicated that biopolymer of poly(3-hydroxy-butyrate) can be used as the matrix polymer for slow release preparations and influence the release of active substance of metsulfuron-methyl in the objects. It is also observed that the highest value of recovery test of active compound was formula 1 : 83.56%, followed by formula 2 : 71.22% and the last was formula 3 : 67.79% The kinetic model of active compound released from microcapsules with correlation coefficient of near by 1 and followed the zero order kinetic obtained from formula 1.


PDF

FIND ARTICLES
SCImago Journal & Country Rank
Recommended Conferences
bornova escort karşıyaka escort osmangazi escort buca escort anne porno fetiş porno anal porno bartın escort burdur escort eskişehir escort escort izmir bursa escort porno escort bayan