Abstract

Measurement of the hypercoagulability state in Sudanese patients with acute myelogenous leukemia in Khartoum state

Author(s): Tarig A. M. Hamid1, Ramy O. M. Hamed ELnil1, Saad A. Saad1, Hossena E. A Suleiman1 Magdi B. Omer1 andMohamed S. Elnour2

Leukemias are a group of disorders characterized by the accumulation of malignant white cells in the bone marrow and blood. This study aimed to measurement the hypercoagulability state in Sudanese patients with acute myelogenous leukemia in Khartoum state between November 2015 and April 2016. The study included 80 individuals, 40 of them were Acute Myelogenous Leukemia patients and 40 from healthy individual as control (Same age and sex with patients). Results were as follow: the mean of fibrinogen level 282.73mg/dl in comparison to control group 270.40mg/dl, Prothrombin PT 14.05 seconds in comparison to control 12.70 seconds. Activated partial thromboplastin time APTT 34.70 seconds in comparison to control 34.30 s and thromboplastin time TT 13.943 seconds, in comparison to control 13.945 seconds. There were no obvious effects on patients with Acute Myelogenous Leukemia in most of parameters when compared with control group which show the lack of relationship between the patients with acute myelogenous leukemia and coagulability (fibrinogen; Prothrombin; activated partial thromboplastin time and thromboplastin time)

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